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Biological Medical Risk Factors

Osteoporosis Biological and Medical Risk Factors


    • Biological Sex – Women have a greater chance of developing osteoporosis.
    • Race – Caucasians and Asians are at greater risk of having osteoporosis.
    • Age – Since bone loss begins at around age 30, the risk of osteoporosis increases with age.
    • Family History – If others in your family have experienced hip or spine fractures or become hunched over as they age, you are at greater risk of experiencing the same symptoms.
    • Body Frame – A thin body frame with low body weight for height will increase the risk of osteoporosis.
    • Post Menopause – Women who are past menopause have reduced estrogen, so their chances of losing bone mass increase.
    • Low Estrogen – There is more risk if women have had a low rate of estrogen over their lifetime. The deficiency can be the result of late onset of puberty/getting their period, early menopause (before 40), or an absence or suppression of menstruation.
    • Medication Use – Certain medications increase the risk of osteoporosis because they contribute to loss of bone mass when used long term. These drugs include steroids, inhaled steroids, anti-epileptic drugs, immunosuppressants, anticoagulants, and thyroid hormone suppressive therapy.
    • Nutritional Conditions – Conditions such as anorexia nervosa, chronic liver disease, malabsorption syndromes, or malnutrition can increase the risk of osteoporosis.
    • Endocrine Disease or Metabolic Causes – These could include thalassemia, diabetes, or hemochromatosis.
  • Other Medical Disorders – Conditions such as Down’s syndrome, mastocytosis, myeloma and some cancers, renal tubular acidosis, rheumatologic disorders, and immobilization add to the risks.